Rifampicin, Fisher BioReagents™

Rifampicin

• An antibiotic used to inhibit synthesis of proteins during recombinant protein expression in bacteria
• Rif inhibits bacterial DNA-dependent RNA polymerase 
• Rif can also be used as a selective agent for some strains
• Mammalian RNA polymerase is not affected

Chemical Identifiers

CAS

13292-46-1

Molecular Formula

C43H58N4O12

Molecular Weight (g/mol)

822.953

InChI Key

FZYOVNIOYYPUPY-HRJPTAQKSA-N

Synonym

Rif

PubChem CID

131839595

SMILES

CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C

Type

Rifampicin

Physical Form

Solid

Melting Point

183°C

Loss on Drying

< 1.0%

Packaging

Amber Glass

Color

Orange

Quantity

1 g

Assay Percent Range

97%

Merck Index

15, 8341

Formula Weight

822.96

Chemical Name or Material

Rifampicin

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
Substances known to cause developmental toxicity in humans. Harmful if swallowed. May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Immediate medical attention is required.

NFPA

Health:2
Flammability:0
Instability:0

Recommended Storage

4°C

SDS

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
Substances known to cause developmental toxicity in humans. Harmful if swallowed. May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Immediate medical attention is required.

NFPA

Health:2
Flammability:0
Instability:0

Recommended Storage

4°C

SDS