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Rimcazole dihydrochloride, Tocris Bioscience™

Catalog No. p-4785434 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

σ2 antagonist. Also DAT inhibitor

Antagonist at σ receptors (IC50 values are 1480 and 386 nM at σ1 and σ2 receptors respectively). Also binds to the dopamine transporter (IC50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo.

Chemical Identifiers

CAS 75859-03-9
Molecular Formula C21H29Cl2N3
Molecular Weight (g/mol) 394.384
InChI Key ZWHRZGHGYMUSRM-VWDRLOGHSA-N
Synonym rimcazole dihydrochloride, rimcazole hydrochloride, bw 234u dihydrochloride, rimcazole hydrochloride usan, rimcazole hcl, 9-3-cis-3,5-dimethyl-1-piperazinyl propyl-9h-carbazole dihydrochloride, 9-3-cis-3,5-dimethyl-1-piperazinyl propyl carbazole dihydrochloride, cis-9-3-3,5-dimethyl-1-piperazinyl propyl-9h-carbazole dihydrochloride, dsstox_cid_25681, dsstox_rid_82704
PubChem CID 53388
IUPAC Name 9-[3-[(3R,5S)-3,5-dimethylpiperazin-1-yl]propyl]carbazole;dihydrochloride
SMILES CC1CN(CC(N1)C)CCCN2C3=CC=CC=C3C4=CC=CC=C42.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 394.39
Percent Purity >98%
Chemical Name or Material Rimcazole dihydrochloride
Recommended Storage Store at +4°C
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