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Rivastigmine tartrate, Tocris Bioscience™

Catalog No. 444050 Shop All R&D Systems Products
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Dual AChE and BChE inhibitor

Rivastigmine tartrate is a cholinesterase inhibitor; inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 ranges are 4.3-4760 nM and 16-238 nM respectively). Rivastigmine increases α-secretase activity and directs APP processing to the non-amyloidogenic pathway. Brain penetrant.

Chemical Identifiers

CAS

129101-54-8

Molecular Formula

C18H28N2O8

Molecular Weight (g/mol)

400.43

MDL Number

MFCD03700731

InChI Key

GWHQHAUAXRMMOT-RWALOXMOSA-N

Synonym

rivastigmine tartrate, rivastigmine bitartrate, sdz-ena 713, rivastigmine hydrogen tartrate, rivastigmine hydrogentartrate, unii-9iy2357jpe, s-3-1-dimethylamino ethyl phenyl ethyl methyl carbamate 2r,3r-2,3-dihydroxysuccinate, rivastigmine tartrate exelon, carbamic acid, ethylmethyl-, 3-1s-1-dimethylamino ethyl phenyl ester, 2r,3r-2,3-dihydroxybutanedioate 1:1

PubChem CID

6918078

ChEBI

CHEBI:64358

IUPAC Name

(2S,3S)-2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate

SMILES

O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C

Specifications

Quantity

50 mg

Formula Weight

400.42

Percent Purity

>99%

Chemical Name or Material

Rivastigmine tartrate

Recommended Storage

Store at Room Temperature

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