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  6. RU 28318, potassium salt, Tocris Bioscience™

RU 28318, potassium salt, Tocris Bioscience™

Catalog No. p-4785483 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent, selective mineralocorticoid receptor antagonist

Potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.

Chemical Identifiers

CAS 76676-34-1
Molecular Formula C25H37KO4
Molecular Weight (g/mol) 440.665
InChI Key HXJITUGMCJCKCE-UYOQDFFISA-M
Synonym 7a,17a-17-hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid, potassium salt
PubChem CID 23677972
IUPAC Name potassium;3-[(7R,8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
SMILES CCCC1CC2=CC(=O)CCC2(C3C1C4CCC(C4(CC3)C)(CCC(=O)[O-])O)C.[K+]

Specifications

Quantity 10 mg
Formula Weight 440.66
Percent Purity >98%
Chemical Name or Material RU 28318, potassium salt

Safety and Handling

Recommended Storage Desiccate at +4°C
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