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Salubrinal, Tocris Bioscience™

Catalog No. 234710 Shop All R&D Systems Products
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective inhibitor of eIF2α dephosphorylation

Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ∽ 15 μM).

Chemical Identifiers

CAS 405060-95-9
Molecular Formula C21H17Cl3N4OS
Molecular Weight (g/mol) 479.804
InChI Key LCOIAYJMPKXARU-VAWYXSNFSA-N
Synonym salubrinal, eif-2alpha inhibitor, salubrinal, n-2,2,2-trichloro-1-3-quinolin-8-yl thioureido ethyl cinnamamide, e-3-phenyl-n-2,2,2-trichloro-1-quinolin-8-ylcarbamothioylamino ethyl prop-2-enamide, 3-phenyl-n-2,2,2-trichloro-1-3-quinolin-8-yl-thioureido-ethyl-acrylamide, 3-phenyl-n-2,2,2-trichloro-1-8-quinolinylamino thioxomethyl amino ethyl-2-propenamide, 2e-3-phenyl-n-2,2,2-trichloro-1-quinolin-8-ylcarbamothioyl amino ethyl acrylamide, e-3-phenyl-n-2,2,2-trichloro-1-8-quinolylcarbamothioylamino ethyl prop-2-enamide, 2e-3-phenyl-n-2,2,2-trichloro-1-8-quinolylamino thioxomethyl amino ethyl prop-2-enamide, 2e-3-phenyl-n-2,2,2-trichloro-1-quinolin-8-yl carbamothioyl amino ethyl prop-2-enamide
PubChem CID 5717801
IUPAC Name (E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide
SMILES C1=CC=C(C=C1)C=CC(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3

Specifications

Quantity 10 mg
Formula Weight 479.81
Percent Purity >99%
Chemical Name or Material Salubrinal

Safety and Handling

Recommended Storage Store at +4°C
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