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SB 265610, Tocris Bioscience™

Catalog No. 272450 Shop All R&D Systems Products
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Potent CXCR2 antagonist

Potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). Inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo.

Chemical Identifiers

CAS

211096-49-0

Molecular Formula

C14H9BrN6O

Molecular Weight (g/mol)

357.171

InChI Key

SEDUMQWZEOMXSO-UHFFFAOYSA-N

Synonym

chembl38182, n-2-bromophenyl-n'-7-cyano-1h-benzotriazol-4-yl urea, 1-2-bromophenyl-3-4-cyano-1h-benzo d 1,2,3 triazol-7-yl urea, 1-2-bromophenyl-3-7-cyano-1h-1,2,3-benzotriazol-4-yl urea, d02jxg, sb hplc, 1-2-bromo-phenyl-3-7-cyano-3h-benzotriazol-4-yl-urea, urea, n-2-bromophenyl-n'-4-cyano-1h-benzotriazol-7-yl, 1-2-bromophenyl-3-7-cyano-2h-1,2,3-benzotriazol-4-yl urea, 1-2-bromophenyl-3-7-cyano-3h-1,2,3-benzotriazol-4-yl urea

PubChem CID

9841667

IUPAC Name

1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea

SMILES

C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br

Specifications

Quantity

50 mg

Formula Weight

357.16

Percent Purity

>98%

Chemical Name or Material

SB 265610

Recommended Storage

Store at Room Temperature
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