SB 505124, Tocris Bioscience™

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively). Selectively inhibits signaling from TGF-β and activin; does not inhibit other ALK family members.

This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.

Chemical Identifiers

CAS

694433-59-5

Molecular Formula

C20H21N3O2

Molecular Weight (g/mol)

335.407

InChI Key

WGZOTBUYUFBEPZ-UHFFFAOYSA-N

Synonym

2-4-benzo d 1,3 dioxol-5-yl-2-tert-butyl-1h-imidazol-5-yl-6-methylpyridine, 2-4-1,3-benzodioxol-5-yl-2-tert-butyl-1h-imidazol-5-yl-6-methylpyridine, 2-4-2h-1,3-benzodioxol-5-yl-2-tert-butyl-1h-imidazol-5-yl-6-methylpyridine, 2-5-1,3-benzodioxol-5-yl-2-1,1-dimethylethyl-1h-imidazol-4-yl-6-methylpyridine, 2-5-2h-1,3-benzodioxol-5-yl-2-tert-butyl-3h-imidazol-4-yl-6-methylpyridine, d0q5uh, 2-5-benzo d 1,3 dioxol-5-yl-2-tert-butyl-1h-imidazol-4-yl-6-methylpyridine, 2-5-benzo 1,3 dioxol-5-yl-2-tert-butyl-3h-imidazol-4-yl-6-methylpyridine, 2-4-1,3-benzodioxol-5-yl-2-1,1-dimethylethyl-1h-imidazol-5-yl-6-methyl-pyridin

PubChem CID

9858940

IUPAC Name

2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine

SMILES

CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4

Quantity

50 mg

Formula Weight

335.4

Percent Purity

>98%

Chemical Name or Material

SB 505124

Recommended Storage

Store at -20°C

Recommended Storage

Store at -20°C