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SC 560, Tocris Bioscience™

Catalog No. 155010 Shop All R&D Systems Products
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Cyclooxygenase-1 (COX-1) inhibitor

Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 μM for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo. Orally active.

Chemical Identifiers

CAS 188817-13-2
Molecular Formula C17H12ClF3N2O
Molecular Weight (g/mol) 352.74
MDL Number MFCD02179214
InChI Key PQUGCKBLVKJMNT-UHFFFAOYSA-N
Synonym 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl-1h-pyrazole, razole, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethylpyrazole, chembl26915, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl pyrazole, lopac-s-2064, d0m5mi, sc hplc, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl-1h-py
PubChem CID 4306515
ChEBI CHEBI:76274
IUPAC Name 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
SMILES COC1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Cl)C=C1)C(F)(F)F

Specifications

Quantity 10 mg
Formula Weight 352.74
Percent Purity >98%
Chemical Name or Material SC 560

Safety and Handling

Recommended Storage Store at +4°C
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