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SCH 23390 hydrochloride, Tocris Bioscience™

Catalog No. 092550 Shop All R&D Systems Products
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Standard selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

Potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). Also an agonist at 5-HT2C receptors in vitro (Ki values are 6.3 - 9.3 nM). Blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors.

Chemical Identifiers

CAS

125941-87-9

Molecular Formula

C17H19Cl2NO

Molecular Weight (g/mol)

324.245

InChI Key

OYCAEWMSOPMASE-XFULWGLBSA-N

Synonym

r +-sch-23390 hydrochloride, sch 23390 hydrochloride, sch-23390 hydrochloride, unii-4s8t3e2f4z, r-+-sch 23390 hydrochloride, 5r-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol hydrochloride, r +-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride, r-+-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride, sch23390 hydrochloride

PubChem CID

11957535

IUPAC Name

(5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride

SMILES

CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl.Cl

Specifications

Quantity

50 mg

Formula Weight

324.24

Percent Purity

>98%

Chemical Name or Material

SCH 23390 hydrochloride

Recommended Storage

Desiccate at +4°C
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