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  8. SCH 58261, Tocris Bioscience™

SCH 58261, Tocris Bioscience™

Catalog No. p-4784526 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

Potent, highly selective A2A antagonist

SCH 58261 is a potent and selective A2A adenosine receptor competitive antagonist (Ki = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A1, A2B and A3 receptors, respectively. Reduces melanoma tumor growth and TGF-β levels in WT and P2X7R-null mice.

Chemical Identifiers

CAS 160098-96-4
Molecular Formula C18H15N7O
Molecular Weight (g/mol) 345.366
InChI Key UTLPKQYUXOEJIL-UHFFFAOYSA-N
Synonym 2-furan-2-yl-7-phenethyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine, chembl17127, 7-2-phenylethyl-5-amino-2-2-furyl-pyrazolo-4,3-e-1,2,4-triazolo 1,5-c pyrimidine, 2-2-furanyl-7-2-phenylethyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine, 5-amino-7-2-phenylethyl-2-2-furyl-pyrazolo 4,3-e-1,2,4-triazolo 1,5-c pyrimidine, 7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine, 2-2-furanyl-7-2-phenylethyl, 4-furan-2-yl-10-2-phenylethyl-3,5,6,8,10,11-hexaazatricyclo 7.3.0.0 2 ,? dodeca-1 9 ,2,4,7,11-pentaen-7-amine, 4-furan-2-yl-10-2-phenylethyl-3,5,6,8,10,11-hexaazatricyclo 7.3.0.0^ 2,6 dodeca-1 9 ,2,4,7,11-pentaen-7-amine, d07esh, d0j8ld
PubChem CID 176408
SMILES C1=CC=C(C=C1)CCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5

Specifications

Quantity 10 mg
Formula Weight 345.36
Percent Purity >99%
Chemical Name or Material SCH 58261

Safety and Handling

Recommended Storage Store at Room Temperature
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