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SCH 79797 dihydrochloride, Tocris Bioscience™
GSA_VA

Catalog No. 159250 Shop All R&D Systems Products
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Potent, selective non-peptide PAR1 antagonist

Potent, selective non-peptide PAR1 receptor antagonist (IC50 = 70 nM). Inhibits haTRAP-induced- but not γ-thrombin-, ADP- or collagen-induced human platelet aggregation. Also selectively blocks PAR1 agonist- or thrombin-induced increases in cytosolic Ca2+ in vascular smooth muscle cells.

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Chemical Identifiers

CAS

1216720-69-2

Molecular Formula

C23H27Cl2N5

Molecular Weight (g/mol)

444.404

InChI Key

NNJTXSQXGHYXAJ-UHFFFAOYSA-N

Synonym

sch 79797 dihydrochloride, n3-cyclopropyl-7-4-1-methylethyl phenyl methyl-7h-pyrrolo 3,2-f quinazoline-1,3-diamine dihydrochloride, n∼3∼-cyclopropyl-7-4-propan-2-yl phenyl methyl-7h-pyrrolo 3,2-f quinazoline-1,3-diamine-hydrogen chloride 1/2

PubChem CID

45073452

IUPAC Name

3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine;dihydrochloride

SMILES

CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N.Cl.Cl

Specifications

Quantity

50 mg

Formula Weight

444.41

Percent Purity

>99%

Chemical Name or Material

SCH 79797 dihydrochloride

Recommended Storage

Desiccate at Room Temperature

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