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SEW 2871, Tocris Bioscience™

Catalog No. p-4784542 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

Cell-permeable, selective S1P1 receptor agonist

Novel, potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo.

Chemical Identifiers

CAS 256414-75-2
Molecular Formula C20H10F6N2OS
Molecular Weight (g/mol) 440.36
MDL Number MFCD00096600
InChI Key OYMNPJXKQVTQTR-UHFFFAOYSA-N
Synonym 5-4-phenyl-5-trifluoromethyl-2-thienyl-3-3-trifluoromethyl phenyl-1,2,4-oxadiazole, s1p1 receptor agonist, sew2871, 5-4-phenyl-5-trifluoromethyl thiophen-2-yl-3-3-trifluoromethyl phenyl-1,2,4-oxadiazole, sphingosine-1-phosphate1 receptor s1p1 agonist, 5-4-phenyl-5-trifluoromethylthiophen-2-yl-3-3-trifluoromethylphenyl-1,2,4-oxadiazole, d0zu0o, sew hplc , solid
PubChem CID 4077460
IUPAC Name 5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
SMILES FC(F)(F)C1=C(C=C(S1)C1=NC(=NO1)C1=CC(=CC=C1)C(F)(F)F)C1=CC=CC=C1

Specifications

Quantity 10 mg
Formula Weight 440.36
Percent Purity >99%
Chemical Name or Material SEW 2871

Safety and Handling

Recommended Storage Store at Room Temperature
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