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  8. SF 11, Tocris Bioscience™

SF 11, Tocris Bioscience™

Catalog No. p-4816703 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

NPY Y2 receptor antagonist

SF 11 is an NPY Y2 antagonist (IC50 = 199 nM). Displays no affinity for Y1 receptor at concentrations up to 35 μM. Causes significant lethality in mice. Displays antidepressant effects in rats. Brain penetrant.

Chemical Identifiers

CAS 443292-81-7
Molecular Formula C27H30N2O2S
Molecular Weight (g/mol) 446.609
InChI Key PMEQBGAGFZDWQX-UHFFFAOYSA-N
Synonym n-4-ethoxyphenyl-4-hydroxy diphenyl methyl piperidine-1-carbothioamide, n-4-ethoxyphenyl-4-hydroxydiphenylmethyl-1-piperidinecarbothioamide, 4-hydroxy-diphenyl-methyl-piperidine-1-carbothioic acid 4-ethoxy-phenyl-amide, n-4-ethoxyphenyl-4-hydroxydiphenylmethyl piperidine-1-carbothioamide, regid_for_cid_2936384, sf hplc, 4-hydroxy diphenyl methyl-n-p-phenetyl-piperidine-1-carbothioamide, 1-4-ethoxyphenyl amino thioxomethyl 4-piperidyl diphenylmethan-1-ol, n-4-ethoxyphenyl-4-hydroxy diphenyl methyl-1-piperidinecarbothioamide, n-4-ethoxyphenyl-4-oxidanyl diphenyl methyl piperidine-1-carbothioamide
PubChem CID 2936384
IUPAC Name N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide
SMILES CCOC1=CC=C(C=C1)NC(=S)N2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O

Specifications

Quantity 10 mg
Formula Weight 446.6
Percent Purity >99%
Chemical Name or Material SF 11

Safety and Handling

Recommended Storage Store at +4°C
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