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Sirtinol, Tocris Bioscience™

Catalog No. 352150 Shop All R&D Systems Products
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective sirtuin family deacetylase inhibitor

Cell-permeable, selective sirtuin deacetylase inhibitor (IC50 values are 38, 68 and 131 μM at SIRT2, Sir2p and SIRT1 respectively) that has no effect on HDAC1 activity. Significantly decreases growth and viability of PCa and HEK293T cells in vitro.

Chemical Identifiers

CAS 410536-97-9
Molecular Formula C26H22N2O2
Molecular Weight (g/mol) 394.47
MDL Number MFCD00810186
InChI Key YUGODMKHHCZZOI-ZVTCDHROSA-N
Synonym 2-e-2-hydroxynaphthalen-1-yl methylidene amino-n-1-phenylethyl benzamide
PubChem CID 19577289
IUPAC Name 2-({[(1Z)-2-oxo-1,2-dihydronaphthalen-1-ylidene]methyl}amino)-N-[(1S)-1-phenylethyl]benzamide
SMILES C[C@H](NC(=O)C1=CC=CC=C1N\C=C1/C(=O)C=CC2=CC=CC=C12)C1=CC=CC=C1

Specifications

Quantity 50 mg
Formula Weight 394.47
Percent Purity >98%
Chemical Name or Material Sirtinol

Safety and Handling

Recommended Storage Store at -20°C
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