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SKF 83566 hydrobromide, Tocris Bioscience™

Catalog No. 158650 Shop All R&D Systems Products
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Potent, selective D1-like antagonist

Potent and selective D1-like dopamine receptor antagonist (Ki∽ 0.56 nM for D1; KB = 2 μM for D2). Also antagonist at the vascular 5-HT2 receptor (Ki = 11 nM). Displays selective inhibition of adenylyl cyclase 2 (AC2); inactive against AC1 or AC5. Centrally active following systemic administration in vivo.

Chemical Identifiers

CAS

108179-91-5

Molecular Formula

C17H19Br2NO

Molecular Weight (g/mol)

413.153

InChI Key

SDQJYYGODYRPBR-UHFFFAOYSA-N

Synonym

skf 83566 hydrobromide, 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo d azepin-7-ol hydrobromide, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol hydrobromide, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-olhydrobromide, 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol hydrobromide, 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol hydrobromide

PubChem CID

23581817

IUPAC Name

8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrobromide

SMILES

CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br.Br

Specifications

Quantity

50 mg

Formula Weight

413.15

Percent Purity

>98%

Chemical Name or Material

SKF 83566 hydrobromide

Recommended Storage

Desiccate at Room Temperature
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