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  7. SNAP 94847 hydrochloride, Tocris Bioscience™

SNAP 94847 hydrochloride, Tocris Bioscience™

Catalog No. p-4784568 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective MCH1 antagonist

Potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding in vivo. Exhibits anxiolytic activity and is orally active.

Chemical Identifiers

CAS 487051-12-7
Molecular Formula C29H33ClF2N2O2
Molecular Weight (g/mol) 515.042
InChI Key DEDUDFNRQKUBRH-UHFFFAOYSA-N
Synonym snap 94847 hydrochloride, n-3-1-4-3,4-difluorophenoxy phenyl methyl-4-piperidinyl-4-methylphenyl-2-methylpropanamide hydrochloride
PubChem CID 56972235
IUPAC Name N-[3-[1-[[4-(3,4-difluorophenoxy)phenyl]methyl]piperidin-4-yl]-4-methylphenyl]-2-methylpropanamide;hydrochloride
SMILES CC1=C(C=C(C=C1)NC(=O)C(C)C)C2CCN(CC2)CC3=CC=C(C=C3)OC4=CC(=C(C=C4)F)F.Cl

Specifications

Quantity 10 mg
Formula Weight 515.03
Percent Purity >98%
Chemical Name or Material SNAP 94847 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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