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Sodium ethoxide, 21% w/w in ethanol, Thermo Scientific Chemicals

Catalog No. AAL13083AE
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Sodium ethoxide, 21% w/w in ethanol is used as a strong base in organic synthesis. It finds application in various chemical reactions such as condensation, esterification, alkoxylation and etherifcation. It is actively involved in Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium ethoxide, 21% w/w in ethanol is used as a strong base in organic synthesis. It finds application in various chemical reactions such as condensation, esterification, alkoxylation and etherifcation. It is actively involved in Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether.

Solubility
Miscible with alcohol.

Notes
Moisture sensitive. It hydrolyzes rapidly into sodium hydroxide in the presence of moist air. Incompatible with water, strong bases, acids, oxidizing agents, alkali metals, strong oxidizing agents, ammonia, acid chlorides, acid anhydrides, reducing agents, peroxides, acids and chlorinated solvents.

Chemical Identifiers

CAS

141-52-6

Molecular Formula

C2H5NaO

Molecular Weight (g/mol)

68.051

MDL Number

MFCD00012417

InChI Key

QDRKDTQENPPHOJ-UHFFFAOYSA-N

Synonym

sodium ethoxide, sodium ethylate, sodium ethanolate, sodiumethoxide, ethoxysodium, ethanol, sodium salt, caustic alcohol, naoet, etona, ethanol, sodium salt 1:1

PubChem CID

2723922

ChEBI

CHEBI:52096

IUPAC Name

sodium;ethanolate

SMILES

CC[O-].[Na+]

Specifications

Density

0.868

Flash Point

20°C (68°F)

Refractive Index

1.3875

Linear Formula

NaOCH2CH3

Quantity

100 mL

UN Number

UN3274

Beilstein

3593646

Sensitivity

Air and moisture sensitive

Merck Index

14,8613

Solubility Information

Miscible with alcohol.

Formula Weight

68.05

Concentration or Composition (by Analyte or Components)

21% w/w in ethanol

Chemical Name or Material

Sodium ethoxide

Hazard Category

H226-H314-H335

Hazard Statement

GHS H Statement
H225-H314
Highly flammable liquid and vapor.
Causes severe skin burns and eye damage.

Precautionary Statement

P201-P202-P210-P233-P235-P235+P410-P240-P241-P242-P243-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

DOTInformation

Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: ALCOHOLATES SOLUTION, N.O.S.

EINECSNumber

205-487-5

TSCA

Yes

Recommended Storage

Ambient temperatures

For Manufacturing and Laboratory Use. Not for beverage use

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