Sodium ethoxide, 21% w/w in ethanol, Thermo Scientific Chemicals

Description

Sodium ethoxide, 21% w/w in ethanol is used as a strong base in organic synthesis. It finds application in various chemical reactions such as condensation, esterification, alkoxylation and etherifcation. It is actively involved in Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium ethoxide, 21% w/w in ethanol is used as a strong base in organic synthesis. It finds application in various chemical reactions such as condensation, esterification, alkoxylation and etherifcation. It is actively involved in Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether.

Solubility
Miscible with alcohol.

Notes
Moisture sensitive. It hydrolyzes rapidly into sodium hydroxide in the presence of moist air. Incompatible with water, strong bases, acids, oxidizing agents, alkali metals, strong oxidizing agents, ammonia, acid chlorides, acid anhydrides, reducing agents, peroxides, acids and chlorinated solvents.

Specifications

Chemical Identifiers

• CAS: 141-52-6
• Molecular Formula: C2H5NaO
• Molecular Weight (g/mol): 68.051
• MDL Number: MFCD00012417
• InChI Key: QDRKDTQENPPHOJ-UHFFFAOYSA-N
• Synonym: sodium ethoxide, sodium ethylate, sodium ethanolate, sodiumethoxide, ethoxysodium, ethanol, sodium salt, caustic alcohol, naoet, etona, ethanol, sodium salt 1:1
• PubChem CID: 2723922
• ChEBI: CHEBI:52096
• IUPAC Name: sodium;ethanolate
• SMILES: CC[O-].[Na+]

• Density: 0.868
• Flash Point: 20°C (68°F)
• Refractive Index: 1.3875
• Linear Formula: NaOCH₂CH₃
• Quantity: 100 mL
• UN Number: UN3274
• Beilstein: 3593646
• Sensitivity: Air and moisture sensitive
• Merck Index: 14,8613
• Solubility Information: Miscible with alcohol.
• Formula Weight: 68.05
• Concentration or Composition (by Analyte or Components): 21% w/w in ethanol
• Chemical Name or Material: Sodium ethoxide

Safety and Handling

Hazard Category	H226-H314-H335
Hazard Statement	GHS H Statement H225-H314 Highly flammable liquid and vapor. Causes severe skin burns and eye damage.
Precautionary Statement	P201-P202-P210-P233-P235-P235+P410-P240-P241-P242-P243-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: ALCOHOLATES SOLUTION, N.O.S.
EINECSNumber	205-487-5
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

For Manufacturing and Laboratory Use. Not for beverage use