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Sonepiprazole, Tocris Bioscience™

Catalog No. p-4817358 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective D4 receptor antagonist

Selective, high affinity antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM). Exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to clozapine (Cat. No. 0444). Brain penetrant and orally available.

Chemical Identifiers

CAS 170858-33-0
Molecular Formula C21H27N3O3S
Molecular Weight (g/mol) 401.525
InChI Key WNUQCGWXPNGORO-NRFANRHFSA-N
Synonym sonepiprazole, isochr-etpip-phso2nh2, sonepiprazole hydrate, chembl69759, 4-4-2-isochroman-1-yl ethyl piperazin-1-yl benzenesulfonamide, 4-4-2-1s-3,4-dihydro-1h-2-benzopyran-1-yl ethyl-1-piperazinyl-benzenesulfonamide, 4-4-2-1s-3,4-dihydro-1h-isochromen-1-yl ethyl piperazin-1-yl benzenesulfonamide, 4-4-2-1s-isochroman-1-yl ethyl piperazin-1-yl benzenesulfonamide hydrate, sonepiprazole inn, d01rae
PubChem CID 133079
IUPAC Name 4-[4-[2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethyl]piperazin-1-yl]benzenesulfonamide
SMILES C1COC(C2=CC=CC=C21)CCN3CCN(CC3)C4=CC=C(C=C4)S(=O)(=O)N

Specifications

Quantity 10 mg
Formula Weight 401.52
Percent Purity >98%
Chemical Name or Material Sonepiprazole

Safety and Handling

Recommended Storage Store at +4°C
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