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Sotalol hydrochloride, 98%, Thermo Scientific Chemicals

Catalog No. AAJ63772MC
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Potent beta adrenergic antagonist

Sotalol hydrochloride is used as a potent beta adrenergic antagonist, prolongs the action potential and increases the refractory period. Sotalol hydrochloride is also considered a non-selective β blocker and a potassium channel blocker with an IC50 of 43 μM.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sotalol hydrochloride is used as a potent beta adrenergic antagonist, prolongs the action potential and increases the refractory period. Sotalol hydrochloride is also considered a non-selective β blocker and a potassium channel blocker with an IC50 of 43 µM.

Solubility
Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Chemical Identifiers

CAS

959-24-0

Molecular Formula

C12H21ClN2O3S

Molecular Weight (g/mol)

308.82

MDL Number

MFCD00242937

InChI Key

VIDRYROWYFWGSY-UHFFFAOYNA-N

Synonym

sotalol hydrochloride, sotalol hcl, betapace, betapace af, sotacor, sotalex, berlex, mead johnson 1999, sorine

PubChem CID

66245

ChEBI

CHEBI:9207

IUPAC Name

hydrogen N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide chloride

SMILES

[H+].[Cl-].CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1

Specifications

Color

White

Quantity

100 mg

Merck Index

14,8728

Solubility Information

Soluble in phosphate buffered saline,DMSO,ethanol,water,and methanol.

Formula Weight

308.82

Percent Purity

98%

Physical Form

Crystalline Powder

Chemical Name or Material

Sotalol hydrochloride

Hazard Category

H315-H319-H335

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

EINECSNumber

213-496-0

RTECSNumber

PB0826000

TSCA

No

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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