Tocris Bioscience™ STO-609 acetate

Description

Selective CaM kinase kinase inhibitor

STO-609 acetate is a selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.

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Specifications

• Chemical Name or Material: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate
• CAS: 1173022-21-3
• Assay Percent Range: >98%
• Quantity: 10 mg
• Solubility: Soluble to 10mM with sonication in DMSO
• Molecular Formula: C₁₉H₁₀N₂O₃.C₂H₄O₂
• Formula Weight: Observed MW: 374.35

For Research Use Only