Sulfamethazine, 99%, Thermo Scientific Chemicals

Description

Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sulfamethazine is an antibacterial. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase.Sulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine. Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid.

Solubility
Soluble in DMSO (56 mg/mL at 25°C), water (<1mg/mL at 25°C), and ethanol (<1mg/mL at 25°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 57-68-1
• Molecular Formula: C12H14N4O2S
• Molecular Weight (g/mol): 278.33
• MDL Number: MFCD00006066
• InChI Key: ASWVTGNCAZCNNR-UHFFFAOYSA-N
• Synonym: sulfamethazine, sulfadimidine, sulfadimethyldiazine, sulfamezathine, sulfadimerazine, sulphamethazine, sulphamezathine, sulfadimezine, sulphadimidine, sulfadimesin
• PubChem CID: 5327
• ChEBI: CHEBI:102265
• IUPAC Name: 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
• SMILES: CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C

• Melting Point: 198°C to 201°C
• Quantity: 25 g
• Solubility Information: Soluble in DMSO (56mg/mL at 25°C),water (<1mg/mL at 25°C),and ethanol (<1mg/mL at 25°C).
• Formula Weight: 278.34
• Percent Purity: 99%
• Chemical Name or Material: Sulfamethazine

Safety and Handling

EINECSNumber	200-346-4
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only