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Sulfanilamide, 98%, Thermo Scientific Chemicals

Catalog No. AAA1300136
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Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.

Solubility
Soluble in water, acetone, ethanol, glycerol, propylene glycol and hydrochloric acid. Insoluble in chloroform, ether, benzene and petroleum ether.

Notes
Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS

63-74-1

Molecular Formula

C6H8N2O2S

Molecular Weight (g/mol)

172.202

MDL Number

MFCD00007939

InChI Key

FDDDEECHVMSUSB-UHFFFAOYSA-N

Synonym

sulfanilamide, sulphanilamide, sulfamine, sulphonamide, p-aminobenzenesulfonamide, sulfonylamide, sulfonamide, p-aminobenzenesulfamide, bacteramid, streptasol

PubChem CID

5333

ChEBI

CHEBI:45373

IUPAC Name

4-aminobenzenesulfonamide

SMILES

C1=CC(=CC=C1N)S(=O)(=O)N

Specifications

Melting Point

163°C to 168°C

Density

1.08

Quantity

500 g

Beilstein

511852

Merck Index

14,8925

Solubility Information

Soluble in water,acetone,ethanol,glycerol,propylene glycol and hydrochloric acid. Insoluble in chloroform,ether,benzene and petroleum ether.

Formula Weight

172.21

Percent Purity

98%

Chemical Name or Material

Sulfanilamide

Hazard Category

H315-H319-H335

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

EINECSNumber

200-563-4

RTECSNumber

WO8400000

TSCA

Yes

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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