Sulfanilamide, MP Biomedicals™

Used as antibacterial agent and to treat vaginal fungal infections. Sulfanilamide, MP Biomedicals is a sulfonamide antibiotic that blocks the synthesis of folic acid by inhibiting the enzyme dihydropteroate synthase. Effective against gram-negative bacter

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. As a sulfonamide antibiotic, it functions by competitively inhibiting enzymatic reactions (i.e., acting as a substrate analogue) involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic reactions that produce folic acid, which acts as a coenzyme in the synthesis of amino acids. By inhibiting dihydropteroate synthase, it blocks the synthesis of folic acid.

Chemical Identifiers

CAS

63-74-1

Molecular Formula

C6H8N2O2S

Molecular Weight (g/mol)

172.202

InChI Key

FDDDEECHVMSUSB-UHFFFAOYSA-N

Synonym

sulfanilamide, sulphanilamide, sulfamine, sulphonamide, p-aminobenzenesulfonamide, sulfonylamide, sulfonamide, p-aminobenzenesulfamide, bacteramid, streptasol

PubChem CID

5333

ChEBI

CHEBI:45373

IUPAC Name

4-aminobenzenesulfonamide

SMILES

C1=CC(=CC=C1N)S(=O)(=O)N

Absorbance

λ max (water): 255–259nm

Melting Point

160°C to 170°C

Density

1.08g/mL (Lit.)

Quantity

100 g

Solubility Information

Soluble in 1g dissolves in 37mL alcohol, 5mL acetone; glycerol, ether, benzene, petroleum ether.

Formula Weight

172.2

Physical Form

Powder

Recommended Storage

Store at Room Temperature (15–30°C).

Recommended Storage

Store at Room Temperature (15–30°C).