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TC-G 1001, Tocris Bioscience™

Catalog No. p-4816750 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

GPR35 agonist; more potent than zaprinast (Cat. No. 0947)

GPR35 agonist (pEC50 values are 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays respectively). Displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast (Cat. No. 0947).

Chemical Identifiers

CAS 494191-73-0
Molecular Formula C17H11FN2O3S
Molecular Weight (g/mol) 342.344
InChI Key SYCKPHBALHXMIR-ZROIWOOFSA-N
Synonym 4-2-2-fluorophenyl azamethylene-4-oxo-1,3-thiazolidin-5-ylidene methyl be nzoic acid, 4-z-2-2-fluoroanilino-4-oxo-1,3-thiazol-5-ylidene methyl benzoic acid, 4-2-2-fluorophenyl amino-4-oxo-5 4h-thiazolylidene methyl benzoic acid, 4-2-2-fluoro-phenylimino-4-oxo-thiazolidin-5-ylidenemethyl-benzoic acid, 4-z-2z-2-2-fluorophenyl imino-4-oxo-1,3-thiazolidin-5-ylidene methyl benzoic acid, 4-2z,5z-2-2-fluorophenyl imino-4-oxo-1,3-thiazolidin-5-ylidene methyl benzoic acid
PubChem CID 5766343
IUPAC Name 4-[(Z)-[2-(2-fluoroanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]benzoic acid
SMILES C1=CC=C(C(=C1)NC2=NC(=O)C(=CC3=CC=C(C=C3)C(=O)O)S2)F

Specifications

Quantity 10 mg
Formula Weight 342.34
Percent Purity >98%
Chemical Name or Material TC-G 1001

Safety and Handling

Recommended Storage Store at +4°C
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