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  8. Temozolomide, Tocris Bioscience™

Temozolomide, Tocris Bioscience™

Catalog No. p-4784673 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA-methylating antitumor agent

DNA methylating, chemotherapeutic agent. Displays antitumor activity against a board spectrum of tumors, including leukemias, lymphomas and solid tumors (IC50 = 5.0 μM for cytotoxicity against mouse TLX5 lymphoma cells). Induces autophagy in malignant glioma cells. Exhibits enhanced activity when used in combination with CHC (Cat No. 5029).

Chemical Identifiers

CAS 85622-93-1
Molecular Formula C6H6N6O2
Molecular Weight (g/mol) 194.154
InChI Key BPEGJWRSRHCHSN-UHFFFAOYSA-N
Synonym temozolomide, methazolastone, temodal, temodar, temozolamide, temozolomidum, 3-methyl-4-oxo-3,4-dihydroimidazo 5,1-d 1,2,3,5 tetrazine-8-carboxamide, temozolomidum latin, temozolodida spanish, temozolodida
PubChem CID 5394
ChEBI CHEBI:72564
IUPAC Name 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
SMILES CN1C(=O)N2C=NC(=C2N=N1)C(=O)N

Specifications

Quantity 10 mg
Formula Weight 194.15
Percent Purity >99%
Chemical Name or Material Temozolomide

Safety and Handling

Recommended Storage Store at Room Temperature
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