tert-Butyl bromoacetate, 98%, Thermo Scientific Chemicals

Description

tert-Butyl bromoacetate is used as an intermediate in the production of dyes, pharmaceuticals, agrochemicals and in organic compounds. It finds application as an alkylating agent. It plays an important role to prepare (2-oxo-4-vinyl-azetidin-1-yl)-acetic acid tert-butyl ester and in collagenase inhibitors synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl bromoacetate is used as an intermediate in the production of dyes, pharmaceuticals, agrochemicals and in organic compounds. It finds application as an alkylating agent. It plays an important role to prepare (2-oxo-4-vinyl-azetidin-1-yl)-acetic acid tert-butyl ester and in collagenase inhibitors synthesis.

Solubility
Miscible with ethanol, chloroform and ethyl acetate. Immiscible with water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 5292-43-3
• Molecular Formula: C6H11BrO2
• Molecular Weight (g/mol): 195.06
• MDL Number: MFCD00000188
• InChI Key: BNWCETAHAJSBFG-UHFFFAOYSA-N
• Synonym: tert-butyl bromoacetate, t-butyl bromoacetate, acetic acid, bromo-, 1,1-dimethylethyl ester, bromoacetic acid tert-butyl ester, tert-butylbromoacetate, acetic acid, bromo-, tert-butyl ester, brch2c o oc ch3 3, acetic acid, 2-bromo-, 1,1-dimethylethyl ester, bromo-acetic acid tert-butyl ester, tert-butylbromacetat
• PubChem CID: 79177
• IUPAC Name: tert-butyl 2-bromoacetate
• SMILES: CC(C)(C)OC(=O)CBr

• Density: 1.33
• Boiling Point: 175°C
• Flash Point: 49°C (120°F)
• Odor: Pungent
• Refractive Index: 1.445
• Linear Formula: BrCH₂CO₂C(CH₃)₃
• Quantity: 10 g
• UN Number: UN2924
• Beilstein: 1753010
• Solubility Information: Miscible with ethanol,chloroform and ethyl acetate. Immiscible with water.
• Formula Weight: 195.06
• Percent Purity: 98%
• Chemical Name or Material: tert-Butyl bromoacetate

Safety and Handling

Hazard Category	H226-H315-H319-H335
Hazard Statement	GHS H Statement H314-H318-H226-H302 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapour. Harmful if swallowed.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber	226-133-6
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only