TGF alpha Monoclonal Antibody (MF9), Biotin, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA513904

Catalog No. PIMA513904

Description

MA5-13904 targets Transforming Growth Factor alpha in WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples. The MA5-13904 immunogen is a 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha.

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Specifications

• Antigen: TGF alpha
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P01134, P01135, P48030
• Gene Symbols: TGFA
• Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: MF9
• Conjugate: Biotin
• Gene: TGFA
• Gene Alias: EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 21802, 24827, 540388, 7039
• Content And Storage: 4° C
• Form: Liquid