TGF beta-1 Polyclonal Antibody, Invitrogen™

TGF beta-1 Antibody, PA1-197, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot.

Supplier:  Thermo Scientific PA1197

Catalog No. PIPA1197

Description

TGF beta-1 Antibody, PA1-197, from Invitrogen. Species Reactivity: Human; Applications: Western Blot.

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: Full length human TGF beta-1 protein (aa 279-390)
Formulation: 100 ug purified antibody (1mg/mL) in PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Synonyms: TGFB, TGFb-1, DPD1, Transforming Growth Factor, Transforming Growth Factor Beta-1, TGF-beta-1, CED
Uniprot Accession: P01137
Entrez GeneID: 7040
Gene Symbol: TGFB1
By Western blot, PA1-197 detects both TGF beta-1 monomer and homodimer.

Specifications

• Antigen: TGF beta-1
• Classification: Polyclonal
• Formulation: 100μg purified antibody (1mg/mL) in PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
• Format: Purified
• Gene Symbols: TGFB1
• Immunogen: Full length human TGF beta-1 protein (aa 279-390)
• Quantity: 100μg
• Type: Primary
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P01137
• Gene Alias: TGFB, TGFb-1, DPD1, Transforming Growth Factor, Transforming Growth Factor Beta-1, TGF-beta-1, CED
• Host Species: Rabbit
• Isotype: IgG
• Storage Requirements: Store at -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 7040