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Enzo Life Sciences Timosaponin AIII (5mg). CAS: 41059-79-4

Supplier: Enzo Life Sciences BMLAP5040005

Induces autophagy in HeLa cells followed by apoptotic cell death (IC50=10μM). This cellular response has been found to be mediated via inhibition of mTORC1 and induction of ER stress (IC50 for BT474 cells=2.5µM and MDAMB231 cells=6µM). The pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both. Purity: ≥96% (HPLC). Solubility: Soluble in DMSO (20 mg/ml). Long Term Storage: -20°C.
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