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Tolbutamide, 98%, Thermo Scientific Chemicals
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
Solubility
Soluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Specifications
Melting Point
128°C to 130°C
Quantity
250 g
Beilstein
1984428
Merck Index
14,9507
Solubility Information
Soluble in chloroform.
Formula Weight
270.35
Percent Purity
98%
Chemical Name or Material
Tolbutamide
Hazard Category
H302-H317
Hazard Statement
GHS H Statement
H302-H317
Harmful if swallowed.
May cause an allergic skin reaction.
Precautionary Statement
P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
EINECSNumber
200-594-3
RTECSNumber
YS4550000
TSCA
Yes
Recommended Storage
Ambient temperatures
RUO – Research Use Only
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