Thermo Scientific Chemicals TRAM 34

 

Supplier:  Thermo Scientific Chemicals J60019MB

Catalog No. AAJ60019MB

Description

TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity. Also used to study its effect on the prevention of vascular restenosis after balloon angioplasty.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 289905-88-0
• Molecular Weight (g/mol): 344.84
• Synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
• SMILES: ClC1=CC=CC=C1C(N1C=CC=N1)(C1=CC=CC=C1)C1=CC=CC=C1

• Molecular Formula: C₂₂H₁₇ClN₂, C22H17ClN2
• InChI Key: KBFUQFVFYYBHBT-UHFFFAOYSA-N
• IUPAC Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole

Specifications

• Quantity: 25 mg
• Content And Storage: 2°C to 8°C
• CAS: 289905-88-0
• Formula Weight: 344.84g/mol
• Melting Point: 145°C to 147°C
• Product Type: Signal Transduction Reagent
• InChI Key: KBFUQFVFYYBHBT-UHFFFAOYSA-N
• IUPAC Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole

• Description: Yellow
• For Use With (Application): TRAM-34 is a potent inhibitor of the intermediate-conductance calcium-activated potassium channel
• Molecular Formula: C₂₂H₁₇ClN₂, C22H17ClN2
• Synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
• Solubility: Soluble in DMSO at 2mg/ml; Insoluble in water
• Form: Powder
• SMILES: ClC1=CC=CC=C1C(N1C=CC=N1)(C1=CC=CC=C1)C1=CC=CC=C1
• Molecular Weight (g/mol): 344.84

Safety and Handling

Recommended Storage : Keep cold