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TRAM 34, Tocris Bioscience™

Catalog No. 294650 Shop All R&D Systems Products
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Potent and highly selective KCa3.1 channel blocker

Potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Chemical Identifiers

CAS

289905-88-0

Molecular Formula

C22H17ClN2

Molecular Weight (g/mol)

344.842

InChI Key

KBFUQFVFYYBHBT-UHFFFAOYSA-N

Synonym

tram-34, 1-2-chlorophenyl diphenylmethyl-1h-pyrazole, tram 34, 1-2-chlorophenyl-diphenylmethyl pyrazole, surecn41130, d03yvq, d05rlr, tram hplc , solid, 1-2-chlorophenyl-diphenyl-methyl pyrazole

PubChem CID

656734

ChEBI

CHEBI:34990

IUPAC Name

1-[(2-chlorophenyl)-diphenylmethyl]pyrazole

SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4

Specifications

Quantity

50 mg

Formula Weight

344.84

Percent Purity

>99%

Chemical Name or Material

TRAM 34

Recommended Storage

Store at +4°C

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