Triethyl phosphite, 98%, Thermo Scientific Chemicals

Description

Triethyl phosphite is used as a ligand in organometallic chemistry and as a reagent in organic synthesis. It is used as reference to phosphoric acid standard in ³¹P NMR spectroscopy. It acts as a reducing agent to prepare 2-phenylindazole from o-nitrobenzylidineaniline as well as reacts with electrophiles to get phosphonates. It forms a stable complex with copper(I) iodide. It finds application in a modified Staudinger reaction for the alkyl bromide to an amine through the azide. Further, it is also used in the preparation of 3-phenyl-2-substituted indoles by reacting with beta-nitro styrenes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triethyl phosphite is used as a ligand in organometallic chemistry and as a reagent in organic synthesis. It is used as reference to phosphoric acid standard in ³¹P NMR spectroscopy. It acts as a reducing agent to prepare 2-phenylindazole from o-nitrobenzylidineaniline as well as reacts with electrophiles to get phosphonates. It forms a stable complex with copper(I) iodide. It finds application in a modified Staudinger reaction for the alkyl bromide to an amine through the azide. Further, it is also used in the preparation of 3-phenyl-2-substituted indoles by reacting with beta-nitro styrenes.

Solubility
Miscible with alcohol and ether. Immiscible with water.

Notes
Air and moisture sensitive. Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 122-52-1
• Molecular Formula: C6H15O3P
• Molecular Weight (g/mol): 166.157
• MDL Number: MFCD00009084
• InChI Key: BDZBKCUKTQZUTL-UHFFFAOYSA-N
• Synonym: phosphorous acid, triethyl ester, triethoxyphosphine, ethyl phosphite, eto 3p, triethylphosphite, phosphorous acid triethyl ester, fosforyn trojetylowy czech, unii-6b2r04s55g, hsdb 895, p oet 3, c2h5o 3p
• PubChem CID: 31215
• IUPAC Name: triethyl phosphite
• SMILES: CCOP(OCC)OCC

• Melting Point: -112°C
• Density: 0.958
• Boiling Point: 155°C to 157°C
• Flash Point: 43°C (109°F)
• Odor: Unpleasant
• Refractive Index: 1.413
• Quantity: 100 mL
• UN Number: UN2323
• Beilstein: 956578
• Sensitivity: Air and moisture sensitive
• Solubility Information: Miscible with alcohol and ether. Immiscible with water.
• Formula Weight: 166.16
• Percent Purity: 98%
• Chemical Name or Material: Triethyl phosphite

Safety and Handling

Hazard Category	H226
Hazard Statement	GHS H Statement H226-H332-H319-H317 Flammable liquid and vapor. Harmful if inhaled. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: TRIETHYL PHOSPHITE
EINECSNumber	204-552-5
RTECSNumber	TH1130000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only