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Triethyl phosphite, 98%, Thermo Scientific Chemicals

Catalog No. AAL00339AP
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Triethyl phosphite is used as a ligand in organometallic chemistry and as a reagent in organic synthesis. It is used as reference to phosphoric acid standard in 31P NMR spectroscopy. It acts as a reducing agent to prepare 2-phenylindazole from o-nitrobenzylidineaniline as well as reacts with electrophiles to get phosphonates. It forms a stable complex with copper(I) iodide. It finds application in a modified Staudinger reaction for the alkyl bromide to an amine through the azide. Further, it is also used in the preparation of 3-phenyl-2-substituted indoles by reacting with beta-nitro styrenes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triethyl phosphite is used as a ligand in organometallic chemistry and as a reagent in organic synthesis. It is used as reference to phosphoric acid standard in 31P NMR spectroscopy. It acts as a reducing agent to prepare 2-phenylindazole from o-nitrobenzylidineaniline as well as reacts with electrophiles to get phosphonates. It forms a stable complex with copper(I) iodide. It finds application in a modified Staudinger reaction for the alkyl bromide to an amine through the azide. Further, it is also used in the preparation of 3-phenyl-2-substituted indoles by reacting with beta-nitro styrenes.

Solubility
Miscible with alcohol and ether. Immiscible with water.

Notes
Air and moisture sensitive. Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

CAS

122-52-1

Molecular Formula

C6H15O3P

Molecular Weight (g/mol)

166.157

MDL Number

MFCD00009084

InChI Key

BDZBKCUKTQZUTL-UHFFFAOYSA-N

Synonym

phosphorous acid, triethyl ester, triethoxyphosphine, ethyl phosphite, eto 3p, triethylphosphite, phosphorous acid triethyl ester, fosforyn trojetylowy czech, unii-6b2r04s55g, hsdb 895, p oet 3, c2h5o 3p

PubChem CID

31215

IUPAC Name

triethyl phosphite

SMILES

CCOP(OCC)OCC

Specifications

Melting Point

-112°C

Density

0.958

Boiling Point

155°C to 157°C

Flash Point

43°C (109°F)

Odor

Unpleasant

Refractive Index

1.413

Quantity

500 mL

UN Number

UN2323

Beilstein

956578

Sensitivity

Air and moisture sensitive

Solubility Information

Miscible with alcohol and ether. Immiscible with water.

Formula Weight

166.16

Percent Purity

98%

Chemical Name or Material

Triethyl phosphite

Hazard Category

H226

Hazard Statement

GHS H Statement
H226-H332-H319-H317
Flammable liquid and vapor.
Harmful if inhaled.
Causes serious eye irritation.
May cause an allergic skin reaction.

Precautionary Statement

P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378q-P501c

DOTInformation

Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: TRIETHYL PHOSPHITE

EINECSNumber

204-552-5

RTECSNumber

TH1130000

TSCA

Yes

Recommended Storage

Ambient temperatures; Store under Argon

RUO – Research Use Only

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