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Trifluoroacetic acid, 99%, Thermo Scientific Chemicals

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.
Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
Specifications
Melting Point
-15°C
Boiling Point
72°C to 73°C
Linear Formula
CF3CO2H
UN Number
UN2699
Beilstein
742035
Merck Index
14,9681
Solubility Information
Miscible with ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
Formula Weight
114.02
Percent Purity
99%
Density
1.48
Hazard Category
H290-H314-H332-H335
Hazard Statement
GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.
Precautionary Statement
P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c
DOTInformation
Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: TRIFLUOROACETIC ACID
EINECSNumber
200-929-3
RTECSNumber
AJ9625000
TSCA
Yes
Recommended Storage
Ambient temperatures
RUO – Research Use Only
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