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Eurofins Discoverx PathHunter U2OS OPRK1 β-Arrestin Cell Line, 2 vials. (93-0234C3)

Supplier:  Eurofins Discoverx 930234C3

Encompass

The PathHunter OPRK1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRK1 and EA-tagged β-Arrestin-2. Activation of OPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Catalog No. 50-200-0022


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