Thermo Scientific Chemicals Ubiquitin E1 Inhibitor, PYR-41

Catalog Number	Mfr. No.	Quantity
AAJ65388MC	Thermo Scientific Chemicals J65388MC	100 mg
AAJ65388MB	Thermo Scientific Chemicals J65388MB	25 mg

Description

PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• PYR-41 is a cell permeable inhibitor of Ubiquitin activating enzyme (E1) with little or no activity against E3, E2, or caspase enzymatic activity

Chemical Identifiers

• CAS: 418805-02-4
• Molecular Formula: C₁₇H₁₃N₃O₇·3H₂O, C17H13N3O7
• Synonym: Ubiquitin-Activating Enzyme E1 Inhibitor; PYR-41

Specifications

• Description: Dark Purple
• For Use With (Application): PYR-41 is a cell permeable inhibitor of Ubiquitin activating enzyme (E1) with little or no activity against E3, E2, or caspase enzymatic activity.
• Molecular Formula: C₁₇H₁₃N₃O₇·3H₂O, C17H13N3O7
• Synonym: Ubiquitin-Activating Enzyme E1 Inhibitor; PYR-41
• Solubility: Soluble in DMSO at 5mg/ml with warming
• Form: Solid
• SMILES: CCOC(=O)C1=CC=C(C=C1)N1NC(=O)C(=CC2=CC=C(O2)[N+]([O-])=O)C1=O
• Molecular Weight (g/mol): 371.31

• Content And Storage: -30°C to -10°C
• CAS: 418805-02-4
• Formula Weight: 425.40g/mol
• Sensitivity: Light Sensitive
• Product Type: Signal Transduction Reagent
• InChI Key: ARGIPZKQJGFSGQ-UHFFFAOYSA-N
• IUPAC Name: ethyl 4-{4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

Safety and Handling

Recommended Storage : Store at -20°C

RUO – Research Use Only