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UCL 2077, Tocris Bioscience™

Catalog No. 266110 Shop All R&D Systems Products
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Slow afterhyperpolarization (sAHP) channel blocker; sub-type selective Kv channel effects

Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine β-hydroxylase knockout mice.

Chemical Identifiers

CAS

918311-87-2

Molecular Formula

C25H22N2

Molecular Weight (g/mol)

350.47

MDL Number

MFCD00585879

InChI Key

PQFNWDHABGBCHB-UHFFFAOYSA-N

Synonym

3-triphenylmethylaminomethyl pyridine, pyridin-3-ylmethyl triphenylmethyl amine, n-trityl-3-pyridinemethanamine, 3-tribenzylaminomethyl pyridine, ucl hplc , solid, 1,1,1-triphenyl-n-pyridin-3-yl methyl methanamine

PubChem CID

24868317

IUPAC Name

[(pyridin-3-yl)methyl](triphenylmethyl)amine

SMILES

C(NC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN=CC=C1

Specifications

Quantity

10 mg

Formula Weight

350.46

Percent Purity

>99%

Chemical Name or Material

UCL 2077

Recommended Storage

Store at Room Temperature
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