UK 383367, Tocris Bioscience™

Description

Potent and selective BMP-1 (PCP) inhibitor

Potent and selective inhibitor of BMP-1 (procollagen C-proteinase; PCP) (IC50 = 44 nM). Selective for BMP-1 over MMPs 1, 2, 3, 9 and 14 (IC50 values are >10,000 nM for listed MMPs).

Specifications

Chemical Identifiers

• CAS: 348622-88-8
• Molecular Formula: C15H24N4O4
• Molecular Weight (g/mol): 324.381
• InChI Key: ARJCBSRIPGJMAD-LLVKDONJSA-N
• PubChem CID: 9818682
• IUPAC Name: 5-[(3R)-6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl]-1,2,4-oxadiazole-3-carboxamide
• SMILES: C1CCC(CC1)CCCC(CC(=O)NO)C2=NC(=NO2)C(=O)N

• Quantity: 1 mg
• Synonym: 5-1r-4-cyclohexyl-1-2-hydroxyamino-2-oxoethyl butyl-1,2,4-oxadiazole-3-carboxamide, 5-2r-5-cyclohexyl-1-hydroxycarbamoyl pentan-2-yl-1,2,4-oxadiazole-3-carboxamide, r-5-6-cyclohexyl-1-hydroxyamino-1-oxohexan-3-yl-1,2,4-oxadiazole-3-carboxamide, d0p2ts, uk hplc, 3r-6-cyclohexyl-n-hydroxy-3-1,2,4-oxadiazol-5-yl hexanamide, 3-aminocarbonyl-?-3-cyclohexylpropyl-n-hydroxy-1,2,4-oxadiazole-5-propanamide, 5-1r-4-cyclohexyl-1-2-hydroxyamino-2-oxoethyl butyl-1,2,4oxadiazole-3-carboxamide, 5-1 r-4-cyclohexyl-1-2-hydroxyamino-2-oxoethyl butyl-1,2,4-oxadiazole-3-carboxamide
• Formula Weight: 324.38
• Percent Purity: >99%
• Chemical Name or Material: UK 383367

Safety and Handling

Recommended Storage

Store at -20°C