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MilliporeSigma™ Upstate In Vivo Shape Reagent (Live Cell RNA Structure Analysis)
Ready to use RNase-free solution with low toxicity to use with live cells for determination of RNA structure
Supplier: MilliporeSigma™ 03310
Description
- High cell-permeability for rapid modification of RNA
- Reacts with all RNA nucleotides for high resolution mapping
- Contains highly pure form of 2-methylnicotinic acid imidazolide (NAI)
- Forms 2'-O-adducts on single stranded regions of RNA that can be detected by Selective 2'-Hydroxyl Acylation Primer Extension (SHAPE)
- NAI rapidly absorbed into cells, formulated to have low levels of toxicity for use with live cells
- Reacts in unbiased fashion with all four RNA nucleotides
- Combination of low toxicity, rapid uptake lack of nucleotide bias enables high resolution RNA structure analysis in variety of living systems
- Packaging: Vial
- Color: Clear, Colourless
Recommended Storage
Store NAI at −20°C in a non-frost-ree freezer protected from light
Specifications
| 2-methylnicotinic acid imidazolide (NAI) in DMSO In Vivo Shape Reagent |
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