Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Azoles
  7. Imidazoles
  8. VER 155008, Tocris Bioscience™

VER 155008, Tocris Bioscience™

Catalog No. p-4816917 Shop All R&D Systems Products
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Hsp70 inhibitor

Novel adenosine-derived inhibitor of Heat Shock Protein 70 (Hsp70) (IC50 = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78; displays selectivity against Hsp90β (IC50 >200 μM for Hsp90β).

Chemical Identifiers

CAS 1134156-31-2
Molecular Formula C25H23Cl2N7O4
Molecular Weight (g/mol) 556.40
MDL Number MFCD18086892
InChI Key ZXGGCBQORXDVTE-UHFFFAOYNA-N
Synonym 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis
PubChem CID 25195348
IUPAC Name 4-({[5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile
SMILES NC1=C2N=C(NCC3=CC(Cl)=C(Cl)C=C3)N(C3OC(COCC4=CC=C(C=C4)C#N)C(O)C3O)C2=NC=N1

Specifications

Quantity 10 mg
Formula Weight 556.4
Percent Purity >98%
Chemical Name or Material VER 155008

Safety and Handling

Recommended Storage Desiccate at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.