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  7. Zatebradine hydrochloride, Tocris Bioscience™

Zatebradine hydrochloride, Tocris Bioscience™

Catalog No. p-4784846 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Blocks hyperpolarization-activated current (If)

Bradycardic agent that produces use-dependent inhibition of hyperpolarization-activated current If (HCN channel) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. Displays negative chronotropic activity in isolated guinea pig atria (EC50 of 13.4 μM).

Chemical Identifiers

CAS 91940-87-3
Molecular Formula C26H37ClN2O5
Molecular Weight (g/mol) 493.041
InChI Key ZRNKXJHEQKMWCH-UHFFFAOYSA-N
Synonym zatebradine hydrochloride, unii-wjb7dyv16a, wjb7dyv16a, ul-fs49, dsstox_cid_25745, dsstox_rid_81090, dsstox_gsid_45745, zatebradine hcl, ul-fs 49
PubChem CID 3045335
IUPAC Name 3-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride
SMILES CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CCC3=CC(=C(C=C3)OC)OC.Cl

Specifications

Quantity 10 mg
Formula Weight 493.04
Percent Purity >98%
Chemical Name or Material Zatebradine hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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