IDE 1, Tocris Bioscience™

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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”

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CAS: 1160927-48-9 Molecular Formula: C15H18N2O5 Molecular Weight (g/mol): 306.318 InChI Key: ABKJCDILEUEJSH-UHFFFAOYSA-N Synonym: ide 1 PubChem CID: 66974738 IUPAC Name: 2-[(6-carboxyhexanoylhydrazinylidene)methyl]benzoic acid SMILES: C1=CC=C(C(=C1)C=NNC(=O)CCCCCC(=O)O)C(=O)O

Cayman Chemical cIs-2-DecenoIc AcId 100mg

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An inhibitor of Ras-mediated signaling that functions by dislodging Ras from the cell membrane thereby rendering it susceptible to proteolytic degradation inhibits the growth of human Ha-ras-transformed Rat1 fibroblasts with an IC50 value of 7 5 UM

Cayman Chemical LIgnocerIc AcId-d3 5mg

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A multi-kinase inhibitor inhibits EphB2 EphA3 Kit FMS VEGFR2/KDR FLT1 FGR Src Lyn BMX and Bcr-Abl in tyrosine kinase-transformed Ba/F3 cells (EC50s 50s 51 and 14 nM respectively) inhibits wild-type and mutant RET kinases (IC50s 24 7 94 2 and 15 8 nM for wild-type RETV804L and RETV804M respectively) reduces growth of NCI-H2286 and HCC-366 cancer cells (GI50s 0 51 and 0 65 M respectively) and RAT1 cells transformed by RETC634R or RETM918T (IC50s 44 and 56 nM respectively) inhibits tumor growth in vivo in a mouse PDX model of EphA2-overexpressing TNBC