Ca2+ channel activator. Induces the release of intracellular Ca2+ . Ryanodine receptors mediate adenine nucleotide, Ca2+ and caffeine-sensitive release of Ca2+ from sarcoplasmic reticulum of cardiac and skeletal muscle and may also mediate intracellular Ca2+ release in neurons. Biphasic effect on sarcoplasmic reticulum calcium channels; Nanomolar levels open the channel and micromolar levels close it. . Formula: C25H35NO9. MW: 493.5. CAS Number: 15662-33-6. MI: 14: 8307. Purity: ≥99% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in methanol or DMSO (>29mg/ml), in 100% ethanol (16mg/ml); slightly soluble in water (warm). Long Term Storage: -20°C