Cayman Chemical 6-methoxy-2-NaphthoIc AcId 1g
A fluorescent copper complex with anticancer activity localizes to mitochondria ex/em 455-495/535 nm respectively inhibits the growth of BxPC-3 AsPC-1 PANC-1 and WI38 pancreatic cancer cells (IC50s 0 74 0 41 0 62 and 2 06 UM respectively) induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in the same cells reduces tumor volume and intratumor apoptosis in an AsPC-1 mouse xenograft model at 1 5 and 3 mg/kg