Cayman Chemical DecorIn Long Isoformhumn100ug
An agonist of a4B2 subunit-containing nAChRs (Ki 43 pM) selective for a4B2 subunit-containing nAChRs over a7 nAChRs (Ki 230 nM) 86Rb flux in IMR-32 cells (EC50 7 nM) induces dopamine release from rat striatal slices (EC50 0.4 nM) induces analgesia in the hot plate test and the Straub-tail response in mice (ED50s 0.005 and 0.02 mg/kg respectively)