Secondary Antibodies
Cayman Chemical GAPDHCTerm RabbIt Monclo 100uL
A cytosine derivative originally found to be an inhibitor of TET1 and TET2 (IC50s 33 and 73 UM respectively in cell-free assays) however it was found that the TET inhibitory activity was due to residual copper in the preparation copper-containing Bobcat 339 reduces DNA 5-hmC levels in HT22 hippocampal neurons at 10 UM but copper-free preparations do not reduce DNA 5-hmC levels in Hep3B cells at 50 UM
Cayman Chemical Akt1CTerm RabbIt Monclon 100uL
A cytosine derivative originally found to be an inhibitor of TET1 and TET2 (IC50s 33 and 73 UM respectively in cell-free assays) however it was found that the TET inhibitory activity was due to residual copper in the preparation copper-containing Bobcat 339 reduces DNA 5-hmC levels in HT22 hippocampal neurons at 10 UM but copper-free preparations do not reduce DNA 5-hmC levels in Hep3B cells at 50 UM
Cayman Chemical IgG2cmouse RabbIt MoncLN 100ug
A cytosine derivative originally found to be an inhibitor of TET1 and TET2 (IC50s 33 and 73 UM respectively in cell-free assays) however it was found that the TET inhibitory activity was due to residual copper in the preparation copper-containing Bobcat 339 reduces DNA 5-hmC levels in HT22 hippocampal neurons at 10 UM but copper-free preparations do not reduce DNA 5-hmC levels in Hep3B cells at 50 UM
Cayman Chemical HIston H4CTerm RabbIt Mo 100ug
A cytosine derivative originally found to be an inhibitor of TET1 and TET2 (IC50s 33 and 73 UM respectively in cell-free assays) however it was found that the TET inhibitory activity was due to residual copper in the preparation copper-containing Bobcat 339 reduces DNA 5-hmC levels in HT22 hippocampal neurons at 10 UM but copper-free preparations do not reduce DNA 5-hmC levels in Hep3B cells at 50 UM
Cayman Chemical CepharnthIn 500mg
A cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation HRP combined with H2O2 causes luminescent peroxidation of luminol can also be oxidized and chemiluminesce by compounds containing iron copper gold and cyanide
Cayman Chemical 3 4 7TrIhydroxyIsoflavon 100mg
A cell-permeable copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC50s 10-34 UM) also causes NF-KB inactivation in an orthotopic pancreatic tumor model using COLO 357 cells
Cayman Chemical LSorbose 50g
A positive allosteric modulator of AMPA receptors (EC50 32 UM) enhances novel object memory (0.1 mg/kg p.o.) and attentional set-shifting (0.3 mg/kg p.o.) in rats reverses a scopolamine-induced deficit in cued fear conditioning (0.1 mg/kg p.o.) in rats
Cayman Chemical AmpIcIlInhydrate 100g
A cell-impermeable metal chelating agent chelates copper iron zinc and manganese as well as calcium magnesium and plutonium has been used as a metal chelating agent in the study of ferroptosis reduces the skeletal plutonium burden and incidence of bone tumors as well as increases survival in a mouse model of intravenous plutonium exposure at 500 mg/kg
Cayman Chemical 5bromo3IndolylDGalacto 500mg
A positive allosteric modulator of GPR68 increases proton-induced cAMP production in HEK293T cells expressing human GPR68 in a reporter assay inhibits proton-mediated calcium release in HEK293T cells expressing human GPR68 at 10 UM impairs contextual but not cued fear conditioning in wild-type but not Gpr68 knockout mice at 10 mg/kg
Cayman Chemical D-PPA 1trIfluoroACTAte500ug
A positive allosteric modulator of GPR68 increases proton-induced cAMP production in HEK293T cells expressing human GPR68 in a reporter assay inhibits proton-mediated calcium release in HEK293T cells expressing human GPR68 at 10 UM impairs contextual but not cued fear conditioning in wild-type but not Gpr68 knockout mice at 10 mg/kg
Cayman Chemical AB-CHMINACA metabolIte M2 10mg
A stilbene glucoside with diverse biological activities scavenges DPPH radicals and inhibits copper-induced lipid peroxidation (IC50s 198 and 19.1 UM respectively) inhibits the proliferation of and induces cell cycle arrest at the S phase in Caco-2 colon cancer cells decreases infarct size cardiomyocyte fibrosis and apoptosis in a mouse model of myocardial ischemia-reperfusion injury induced by LAD coronary artery occlusion at 40 mg/kg per day
Cayman Chemical DorzolamIdehydrochlorIde 250mg
A stilbene glucoside with diverse biological activities scavenges DPPH radicals and inhibits copper-induced lipid peroxidation (IC50s 198 and 19.1 UM respectively) inhibits the proliferation of and induces cell cycle arrest at the S phase in Caco-2 colon cancer cells decreases infarct size cardiomyocyte fibrosis and apoptosis in a mouse model of myocardial ischemia-reperfusion injury induced by LAD coronary artery occlusion at 40 mg/kg per day
Cayman Chemical AB-CHMINACA metabolIte M4 10mg
A stilbene glucoside with diverse biological activities scavenges DPPH radicals and inhibits copper-induced lipid peroxidation (IC50s 198 and 19.1 UM respectively) inhibits the proliferation of and induces cell cycle arrest at the S phase in Caco-2 colon cancer cells decreases infarct size cardiomyocyte fibrosis and apoptosis in a mouse model of myocardial ischemia-reperfusion injury induced by LAD coronary artery occlusion at 40 mg/kg per day
Cayman Chemical L-TetrahydropalmatIn 25mg
An mGluR5 PAM induces calcium mobilization in HEK293 cells expressing human mGluR5 (EC50 260 nM) selective for mGluR5 over mGluR1-4 and mGluR6-8 at 10 M reverses amphetamine-induced hyperlocomotion in rats (ED50 23 mg/kg) indicating antipsychotic-like activity increases levels of c-fos and expression of BDNF Arc/Arg3 1 syntaxin 1A and PSD-95 in the hippocampus in the BACHD mouse model of Huntingtons disease at 3 mg/kg improves object location memory in the novel object location test and associative memory in the cued fear conditioning test in the BACHD mouse model at 3 mg/kg
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