Secondary Antibodies
Secondary Antibodies
Biotang Inc MUS ANTI HUM; Transforming Growth Factor-beta
MUS ANTI HUM; Transforming Growth Factor-beta
Biotang Inc MUS ANTI HUM; Transforming Growth Factor Beta Induced
MUS ANTI HUM; Transforming Growth Factor Beta Induced
Biotang Inc PAB; RAB; Anti Human Transforming Growth Factor-beta 2
PAB; RAB; Anti Human Transforming Growth Factor-beta 2
Cayman Chemical PyropheophorbIde a 50mg
An inhibitor of Ras-induced malignant transformation that prevents anchorage-independent growth of oncogene transformed fibroblasts blocks Ras/Rac-induced membrane ruffling in REF-52 fibroblasts (5-25 UM) with little effect on Ras-induced ERK and JNK kinase activity
Cayman Chemical TaurohyocholIc AcIdodIM10mg
A bicyclic guanidine base that can be used as a catalyst for a variety of base-mediated organic transformations
Cayman Chemical PyropheophorbIde a 10mg
An inhibitor of Ras-induced malignant transformation that prevents anchorage-independent growth of oncogene transformed fibroblasts blocks Ras/Rac-induced membrane ruffling in REF-52 fibroblasts (5-25 UM) with little effect on Ras-induced ERK and JNK kinase activity
Cayman Chemical D-CycloserIn 500mg
An apoptosis inducer that inhibits the mitochondrial F1FO ATPase (Ki 4-5 UM) selectively kills transformed glial cells without significantly affecting untransformed cells
Cayman Chemical L-SelenocystIn 50mg
A potent selective ATP-competitive inhibitor of c-Met (IC50 20 nM) induces apoptosis and cell cycle arrest in transformed Ba/F3 cells and cancer cell lines
Cayman Chemical ANTIBODY AP-III-a4 10mg
A selective inhibitor of PFKFB3 (IC50 207 nM) rapidly induces apoptosis in transformed cells suppresses glucose uptake and growth of Lewis lung carcinomas in syngeneic mice and yields antitumor effects in human xenograft models of cancer in athymic mice
Cayman Chemical RabbIt ntI-Goat IgGDyLIght 1mg
A selective Ras inhibitor that blocks H-Ras GTP binding to c-Raf-1 (Ki 149 UM) inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 1.4-2 UM)
Cayman Chemical Goat ntI-RabbIt IgGSureLIg 1mg
A selective Ras inhibitor that blocks H-Ras GTP binding to c-Raf-1 (Ki 149 UM) inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 1.4-2 UM)
Cayman Chemical Goat ntI-RabbIt IgGDyLIght 1mg
A selective Ras inhibitor that blocks H-Ras GTP binding to c-Raf-1 (Ki 149 UM) inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 1.4-2 UM)
Cayman Chemical THUNDRTotal JNK123 TRFR 4800
A DOT1L inhibitor (IC50 0.3 nM) selective for DOT1L over a panel of 12 additional protein methyltransferases DNMT1 and a panel of 29 receptors and ion channels reduces H3K79me2 levels in MCF-10A breast cancer cells (IC50 8.8 nM) selectively reduces the viability of isolated human cord blood cells transformed with an MLL-AF9 fusion oncogene over those transformed with a TLS-ERG fusion oncogene at 1 and 5 UM adoptive transfer of isolated human CD3 T cells pre-incubated with SGC0946 (0.5 UM) prevents weight loss increases survival and reduces hepatic and colonic lymphocyte infiltration in a xenogeneic mouse model GVHD
Cayman Chemical THUNDRTotal JNK123 TRFR 9600
A DOT1L inhibitor (IC50 0.3 nM) selective for DOT1L over a panel of 12 additional protein methyltransferases DNMT1 and a panel of 29 receptors and ion channels reduces H3K79me2 levels in MCF-10A breast cancer cells (IC50 8.8 nM) selectively reduces the viability of isolated human cord blood cells transformed with an MLL-AF9 fusion oncogene over those transformed with a TLS-ERG fusion oncogene at 1 and 5 UM adoptive transfer of isolated human CD3 T cells pre-incubated with SGC0946 (0.5 UM) prevents weight loss increases survival and reduces hepatic and colonic lymphocyte infiltration in a xenogeneic mouse model GVHD
Cayman Chemical ANTIBODY MK-5108 5mg
A cell-permeable reversible inhibitor of a mitochondrial glutaminase splice variant glutaminase C (IC50 2 5 UM) which is commonly found in cancer cells blocks transformation induced by Rho GTPases and inhibits the proliferation of cancer cell lines without affecting normal cells