Mouse Secondary Antibodies
Mouse Secondary Antibodies
Biotang Inc MUS ANTI HUM; Calcium and Integrin Binding 1
MUS ANTI HUM; Calcium and Integrin Binding 1
Cayman Chemical aCardIac ActInTerm Rabb 100uL
An isomer of vitamin D3 increases tibia ash weight and bone mineralization in vitamin D-deficient chicks at 1 3 and 10 Ug/day induces intestinal calcium transport and bone calcium mobilization in anephric rats fed a low-calcium and vitamin D-deficient diet at 25 Ug/animal
Cayman Chemical ANTIBODY MK-8745 50mg
A divalent cation ionophore commonly used to facilitate the movement of Ca2 into cells triggering the activation of intracellular calcium-dependent pathways also used to produce apoptosis through calcium overload as occurs during hypoxic or oxidative stress
Cayman Chemical 24a-ethyl Cholesterol 5mg
An OPN4 receptor antagonist (Ki 16 nM) inhibits light-induced calcium transients in CHO cells expressing human OPN4 (IC50 665 nM) reverses light-induced calcium influx in rat ipRGCs at 10 UM reduces light-induced pupil constriction in mice at 30 mg/kg
Cayman Chemical TulathromycIn A 10mg
A TRPV4 agonist that has been reported to elicit calcium influx in HEK cells expressing mouse or human TRPV4 (EC50s 18 and 2 1 nM respectively) used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone
Cayman Chemical ANTIBODY 15-OxoETE 250ug
A positive allosteric modulator of mGluR5 receptors potentiates glutamate-induced calcium mobilization in MCB3901 cells expressing human mGluR5 (EC50 52 nM) increases rat hippocampal mGluR5 receptor occupancy (ED50 13 mg/kg) increases wakefulness and decreases NREM and REM sleep in rats at 0 3 1 and 3 mg/kg
Cayman Chemical a-HydroxyglutarIc AcId 10mg
A potent OX1R antagonist (Ki 26.9 nM in a calcium mobilization assay) selective for OX1R over OX2R (Kds 21.7 and 1704 nM respectively in a radioligand binding assay) co-perfusion with human OX1R in rat ventral tegmental area inhibits OX1R-induced glutamate and dopamine elevations reduces cocaine-seeking behavior in rats
Cayman Chemical DI-a-lInolenIn 10mg
A monounsaturated fatty acid a major component of membrane phospholipids inhibits collagen-stimulated platelet aggregation at 10 Ug/ml inhibits fMLF-induced neutrophil aggregation and degranulation at 5 UM induces release of intracellular calcium in human platelets at 60 UM increases TNF-a IL-8 IL-6 and IL-1B production neutrophil accumulation and apoptotic and necrotic cell death in mouse lung
Cayman Chemical a-LInolenIc AcId 50mg
A chloride channel inhibitor inhibits VRAC in HEK293 cells and chloride conductance in washed isolated human erythrocytes (IC50s 0.4 and 0.6 UM respectively) inhibits calcium-activated chloride currents in Ehrlich-Lettre ascites carcinoma cells (IC50s 2.11 and 0.7 UM at 95 and -50 mV respectively) reduces the proliferation of Ehrlich-Lettre ascites cells and inhibits IFN-Y-induced NO production in BV-2 microglia (IC50s 0.52 and 3.7 UM respectively)
Cayman Chemical UNC-CA2-103 1mg
A cardiac-specific myosin activator selectively activates human cardiac S1 myosin at UM increases sarcomere activity of isolated porcine left ventricular and atrial myofibrils (AC50s 6 and 3.6 UM respectively) increases calcium sensitivity of isolated porcine skinned left ventricular and atrial fibers at a concentration of 3 UM prolongs systolic ejection time and improves left ventricular ejection fraction and stroke volume in a dog model of heart failure at 2-3 mg/kg
Cayman Chemical CorylIfol A 10mg
An OX2R antagonist (Ki 1.1 nM) selective for OX2R over OX1R (Ki 900 nM) inhibits orexin-A- and orexin-B-induced calcium mobilization (IC50s 8.8 and 7.9 nM respectively) and increases orexin-A- and orexin-B-induced inositol phosphate accumulation (EC50s 1.1 and 2.4 nM respectively) in CHO(dHFr-) cells expressing recombinant human OX2R reduces spontaneous locomotor activity and orexin-B-induced hyperlocomotion in mice at 10-300 mg/kg
Cayman Chemical UNC-CA2-103 5mg
A cardiac-specific myosin activator selectively activates human cardiac S1 myosin at UM increases sarcomere activity of isolated porcine left ventricular and atrial myofibrils (AC50s 6 and 3.6 UM respectively) increases calcium sensitivity of isolated porcine skinned left ventricular and atrial fibers at a concentration of 3 UM prolongs systolic ejection time and improves left ventricular ejection fraction and stroke volume in a dog model of heart failure at 2-3 mg/kg
Cayman Chemical SenkyunolIde A 10mg
An FFAR1 (GPR40) partial agonist induces calcium mobilization in CHO cells expressing FFAR1/GPR40 but not FFAR2/GPR43 FFAR3/GPR41 or FFAR4/GPR120 (EC50s 0.0135 10 10 and 10 UM respectively) induces insulin secretion in MIN6 pancreaticBcells and isolated mouse islets (EC50s 0.0048 and 0.142 UM respectively) decreases plasma glucose levels and increases plasma levels of insulin in Zucker fa/fa rats at 0.3 1 and 3 mg/kg decreases plasma glucose and increases plasma insulin levels in a mouse model of diabetes induced by a high-fat diet and streptozotocin
Cayman Chemical Kukoamn A 10mg
An NSAID and COX inhibitor (IC50s 3 and 9.3 UM for human COX-1 and COX-2 respectively) inhibits TNF-a-induced increases in COX-2 levels and NF-KB activation in HT-29 colon cancer cells in a concentration-dependent manner inhibits fMLP- or A23187-induced calcium influx in PMN (IC50s 29 and 14 UM respectively) activates various ion channels including TRPC6 and KCa1.1 inhibits various ion channels including TRPC3 and CFTR reduces increases in intestinal fluid secretion and intestinal barrier disruption in mice infected with the El Tor variant of V. cholerae at 20 mg/kg